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HelpTest Code LAB10325 Cyclosporine A
Department
SEND OUTS
Reference Lab Test Number
CYCLO
Refer To
Primary Collection Container
Lavender 4 mL (K3EDTA)
Transport
Whole blood refrigerated
Preferred Transport Temperature
Refrigerated
Processing
Send 1.0 mL whole blood refrigerated. CAUTION: The complexity of the clinical state, individual differences in sensitivity to the immunosuppressive and nephrotoxic effects of cyclosporine, the co-administration of other immunosuppressants, the type of transplant and a number of other factors will cause different requirements for optimal whole blood levels of cyclosporine. The reference ranges below are general guidelines and apply to
trough specimens drawn just prior to a.m. dose.
Stability
Ambient: 24 hr
Refrigerated: 7 days
Frozen: Unacceptable
Minimum Testing Volume
0.2 mL
Reference Range
100-400 ng/mL
Toxic: >700 ng/mL
Organ Kidney (W/ Everolimus)
Post Transplant (Months)
Up to 1 - 100-200 ng/mL
2-3 75-150 ng/mL
4-5 50-100 ng/mL
6-12 25-50 ng.mL
Heart
Up to 3 350-525
≥4 145-350
Liver 290-525
Methodology
Liquid Chromatography/Tandem Mass Spectrometry
Performed
Monday – Saturday
Reported
2-3 days
CPT Codes
80158
Additional Information
CAUTION: The complexity of the clinical state, individual differences in sensitivity to the immunosuppressive and nephrotoxic effects of cyclosporine, the co-administration of other immunosuppressants, the type of transplant, and a number of other factors will cause different requirements for optimal whole blood levels of cyclosporine. The reference ranges below are general guidelines and apply to trough specimens drawn just prior to a.m. dose.