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HelpTest Code LAB11286 Catecholamines, Fractionated - 24 Hour Urine
Department
SEND OUTS
Reference Lab Test Number
UCATE
Collection Requirements
24 hour urine collection: The bladder must be emptied at the time the collection is to begin, and this urine is discarded. Thereafter all urine must be collected until the end of the scheduled time.
Preferred method of collection for 24 hour collection: Collect urine with 25 mL of 6N HCl at start of collection to maintain pH between 1 and 3. Refrigerate urine during collection (critical). Mix the collection well before removing aliquot and refrigerate aliquot.
Alternate method of collection for 24 hour collection: Refrigerate urine during collection (critical) and add 25 mL 6N HCl to the entire collection within 4 hours of completing collection. Mix the collection well before checking the pH. Ensure pH is between 1 and 3. Record total volume on test request and on container label. Send 25 mL aliquot (10 mL minimum). Refrigerate.
If other tests are ordered requiring pH other than 1-3 you may acidify a 25.0 mL aliquot of the 24 hour collection.
Refer To
Primary Collection Container
24 HR Urine container
Alternate Collection Container
Yellow Urine Vacutainer (No Additive)
Transport
Urine refrigerated
Preferred Transport Temperature
Refrigerated
Processing
Send a 25 mL acidified aliquot in a screw-capped plastic urine cup. Record total volume on test requisition and specimen label.
Stability
With Preservatives:
Ambient: 72 hours
Refrigerated: 1 week
Frozen: 1 Month
Minimum Testing Volume
10 mL
Reference Range
Epinephrine:
Age Epinephrine mcg/day <1 year 0-3 1 year 0-4 2-3 years 0-6 4-9 years 0-10 10-15 years 0-20 ≥16 years 0-20
Norepinephrine:
Age Range <1 year 0-10 mcg/day 1 year 1-17 mcg/day 2-3 years 4-29 mcg/day 4-9 years 8-45 mcg/day 10-15 years 13-65 mcg/day ≥16 years 15-80 mcg/day
Total (N+E):
Age Range <1 year 0-13 mcg/day 1 year 1-21 mcg/day 2-3 years 4-35 mcg/day 4-9 years 8-55 mcg/day 10-15 years 14-85 mcg/day ≥16 years 15-100 mcg/day
Dopamine:
Age Range <1 year 0-85 mcg/day 1 year 10-140 mcg/day 2-3 years 40-260 mcg/day 4-9 years 65-400 mcg/day 10-15 years 65-400 mcg/day ≥16 years 65-400 mcg/day
Creatinine:
Male: 1.0-2.0 g/24 hours Female: 0.8-1.8 g/24 hours
Methodology
High Performance Liquid Chromatography
Performed
Monday-Friday
Reported
6 days
CPT Codes
82384, 82570
Additional Information
NOTE: Medications that may interfere with catecholamines and metabolites include amphetamines and ampehtamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, carbidopa-levopa (Sinemet), clonidine, dexamethasone, diuretics, ethanol, isoproterenol, methyldopa (Aldomet), MAO inhibitors, nicotine, nose drops, propafenone (Rythmol), reserpine, theophylline, tricyclic antidepressants, and vasodilators.