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Test Code LAB20082 Proinsulin, Plasma

Important Note

Collect at POB only, see collection instructions.

Reporting Name

Proinsulin, P

Useful For

As part of the diagnostic workup of suspected insulinoma


As part of the diagnostic workup of patients with suspected prohormone convertases1/3 deficiency


As part of the diagnostic workup of patients with suspected proinsulin variations

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Plasma EDTA

Specimen Required

Patient Preparation:

1. Patient should be fasting for 8 hours.

2. Infants under 2 years of age should fast a maximum of 6 hours.

Collection Container/Tube: Ice-cooled, lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: After collection, place the whole blood on ice for at least 10 minutes, then centrifuge at refrigerated temperature.

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen 30 days

Reference Values

3.6-22 pmol/L

Day(s) and Time(s) Performed


Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
PINS Proinsulin, P 27882-0


Result ID Test Result Name Result LOINC Value
80908 Proinsulin, P 27882-0

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Method Name

Electrochemiluminescent Assay

Secondary ID