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Test Code LAB20423 SARS-Cov-2 Total Antibody Screen Rflx to SARS-CoV-2 IgG



Collection Requirements

Suggest to be drawn greater than 14 days post exposure or onset of symptoms

Primary Collection Container

Gold (SST)

Alternate Collection Container

Yellow Microtainer SST


Refrigerated up to 7 days

Preferred Transport Temperature



Centrifuge and refrigerate


Refrigerated: 7 days

Minimum Testing Volume

2 mL

Reference Range



Total Antibody – Immunoassay

SARS-CoV-2 IgG – Enzyme-Linked Immunosorbent Assay (ELISA)


Mon-Fri 6 AM-2:30 PM


3-5 days

CPT Codes

86769 Reflex to: 86769

Unacceptable Conditions

Grossly hemolyzed. Grossly Lipemic

Additional Information


Healthcare Providers Fact Sheet

For Recipients Fact Sheet


Healthcare Providers Fact Sheet

For Recipients Fact Sheet


Healthcare Providers Fact Sheet

For Recipients Fact Sheet

Serology Test Results:

Negative or Non-Reactive Test results:

• A Negative or Non-Reactive result indicates there are no detectable antibodies to SARS-CoV-2.

• Negative Antibody results do not rule out current or recent SARS-CoV-2 infection. If SARS-CoV-2 infection is suspected follow up with Molecular PCR testing for Covid-19.

• False-negative Antibody results may occur in serum collected too soon after symptom onset or exposure. Typically, the majority of patients seroconvert within 1 to 3 weeks.

• Over time, antibody titers may decline and eventually become negative.

• A negative result may be found in patients with a depressed immune response including the elderly, immunocompromised or immunosuppressed patient.

Equivocal Results:

• Equivocal results should only be interpreted as initial evidence for detection of antibodies to SARS-CoV-2. Additional testing is recommended for equivocal test results. Serological evidence is best obtained by testing of paired acute and convalescent phase samples obtained several weeks apart.

Positive or Reactive Test Results:

• A Positive or Reactive result indicates that antibodies were detected to SARS-CoV-2.

• A Positive or Reactive results indicates likely past exposure or past infection by SARS-CoV-2.

• Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E.

• Protective immunity cannot be inferred based on these results alone.

• The duration and relative amount of antibodies remaining in the blood following COVID-19 is unknown.

• Positive Serological results should not be used to diagnose recent SARS-CoV-2 Infection; If SARS-CoV-2 infection or recent exposure is suspected follow up with Molecular PCR testing for Covid-1