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HelpTest Code LAB20726 Synovasure Comprehensive PJI Test Panel
Department
SEND OUTS
Reference Lab Test Number
SYN
Collection Requirements
Submit synovial fluid in 13×75mm red topped, evacuated vacuum tubes with NO additive.
Collection kits can be obtained from the Covenant Laboratory Send out department at 583-6717.
Refer To
Zimmer BiometPrimary Collection Container
Collection kit
Transport
Refrigerated
Preferred Transport Temperature
Refrigerated
Stability
Ambient: 3 days
Refrigerated: 7 days
Minimum Testing Volume
1 ml
Reference Range
By Report
Methodology
Synovasure™ LDT targets and measures levels of alpha defensins present in the synovial fluid of infected joints using immunoassay technology
Performed
Monday – Thursday
Reported
3 days
CPT Codes
-86140, 84311, 83516
Additional Information
The Synovasure™ PJI test was developed specifically for the diagnosis of periprosthetic joint infection (PJI). Synovasure™ PJI is a laboratory developed test (LDT) for the detection of infection in the synovial fluid (joint fluid) of patients experiencing pain and/or inflammation in a joint. Synovasure™ is a panel of tests. The panel capitalizes on the diagnostic characteristics of alpha-defensin, and also includes an adjustment for samples with significant amounts of bloody contamination or hemolysis. Furthermore, the inclusion of a synovial fluid CRP test in the Synovasure™ PJI panel provides for the identification of samples that are most likely to represent false positive results due to confounding conditions such as metallosis. Synovasure™ PJI maintains its diagnostic performance even among patients with systemic inflammatory diseases, patients on antibiotics and patients experiencing the effects of metal products.