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Test Code LAB20994 14-3-3 Protein, CSF (Prion Disease)

Department

Send Outs

Reference Lab Test Number

CSFPD

Collection Requirements

Collect Cerebrospinal fluid (CSF) - do not send the first 2.0 mL of CSF flow from tap. Send 2.0 mL CSF frozen immediately after collection, in a sterile screw capped plastic vial. Please call client service for a form. The ordering physician name and phone number are required by the National Prion Lab.

Refer To

Warde Medical Laboratory

Primary Collection Container

CSF Tube

Transport

CRITICAL FROZEN

Preferred Transport Temperature

CRITICAL FROZEN

Processing

The patient must be 12 years of age or older.

Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: Indefinitely

Minimum Testing Volume

1.0 mL

Reference Range

RT-QuIC (CSF): No Change
T-tau protein (CSF): No Change
14-3-3 GAMMA (CSF): 173 - 1999 AU/mL
Likelihood of prion disease: No Change

Methodology

Qualitative Enzyme-Linked Immunosorbent Assay

Performed

Varies

Reported

8-10 days

CPT Codes

83520 x2
0035U

Unacceptable Conditions

Bloody and insufficient sample quantity. Samples that are colored or contain blood cannot be performed for RT-QulC and 14-3-3 GAMMA.