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Test Code MAPTZ MAPT Gene, Sequence Analysis, 7 Exon Screening Panel, Varies

Useful For

Aiding in the diagnosis of frontotemporal dementia, progressive supranuclear palsy, corticobasal degeneration, and dementia with epilepsy

 

Distinguishing the diagnosis of frontotemporal dementia from other dementias, including Alzheimer dementia

 

Identifying individuals who are at risk of frontotemporal dementia

Method Name

Polymerase Chain Reaction (PCR)/DNA Sequencing Analysis

Reporting Name

MAPT Gene, Sequencing Analysis

Specimen Type

Varies


Shipping Instructions


Specimen preferred to arrive within 96 hours of draw.



Specimen Required


Patient Preparation: A previous bone marrow transplant from an allogenic donor will interfere with testing. Call 800-533-1710 for instructions for testing patients who have received a bone marrow transplant.

Specimen Type: Whole blood

Container/Tube:

Preferred: Lavender top (EDTA) or yellow top (ACD)

Acceptable: Any anticoagulant

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send specimen in original tube.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Frozen 
  Refrigerated 

Reject Due To

All specimens will be evaluated by Mayo Clinic Laboratories for test suitability.

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Performed weekly; Varies

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81406-MAPT (microtubule-associated protein tau) (eg, frontotemporal dementia), full gene sequence

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MAPTZ MAPT Gene, Sequencing Analysis 41092-8

 

Result ID Test Result Name Result LOINC Value
53964 Result Summary 50397-9
53965 Result 82939-0
53966 Interpretation 69047-9
53967 Additional Information 48767-8
53968 Specimen 31208-2
53969 Source 31208-2
53970 Released By 18771-6

Secondary ID

35475

Forms

1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available in Special Instructions:

- Informed Consent for Genetic Testing (T576)

- Informed Consent for Genetic Testing (Spanish) (T826)

2. Molecular Genetics: Neurology Patient Information in Special Instructions

3. If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.