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Test Code MISC1WARDEBSEPL Bupropion and Metabolite, S/P

Department

Send Outs

Reference Lab Test Number

BSEPL

Collection Requirements

CRITICAL FROZEN

Refer To

Warde medical Laboratory

Primary Collection Container

Red (No Gel)

Alternate Collection Container

Lavender 6 mL (K3EDTA)

Green (Sodium Heparin)

Transport

Serum Frozen

Preferred Transport Temperature

Frozen

Processing

Centrifuge, separate serum from cells and freeze within 2 hours. Send 2.0 mL serum frozen in a screw-capped vial.

Stability

Room temperature: Unacceptable

Refrigerated: Unacceptable

Frozen: 14 days

Minimum Testing Volume

0.5 mL

Reference Range

Bupropion:

Therapeutic Range: 10 – 100 ng/mL

Toxic Level: ≥ 400 ng/mL

Hydroxybuproprion:

Therapeutic Range: 850 – 1500 ng/mL

Toxic Level: ≥ 2000 ng/mL

Methodology

Quantitative Liquid Chromatography – Tandem Mass Spectrometry

Performed

Monday

Reported

10-12

CPT Codes

80338 (G0480)

Unacceptable Conditions

SST tube, sodium citrate, ACD A or B, whole blood