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Test Code MISC2MAYOASFRU Arsenic Fractionation, Random, Urine

Reporting Name

Arsenic Fractionation, Random, U

Useful For

Diagnosis of arsenic intoxication in random urine specimens

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Patient Preparation:

1. Patient should not eat seafood for a 48-hour period prior to start of collection.

2. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies:

Urine Tubes, 10 mL (T068)

Aliquot Tube, 5 mL (T465)

Collection Container/Tube: Clean, plastic urine collection container

Submission Container/Tube: Plastic, 5-mL tube (T465) or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.


Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

TOTAL ARSENIC

<20 mcg/L

 

INORGANIC ARSENIC

<20 mcg/ L

 

Reference values apply to all ages.

 

*Biological exposure indices (BEI) for arsenic is 35 mcg/L based on the concentration of inorganic arsenic plus methylated metabolites.

Day(s) and Time(s) Performed

Monday through Friday; 8 a.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82175

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ASFRU Arsenic Fractionation, Random, U 54454-4

 

Result ID Test Result Name Result LOINC Value
32311 Inorganic Arsenic (Toxic) 12481-8
32312 Organic Arsenic (Non-Toxic) 53778-7
113134 Total Arsenic 5586-3

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Ion Chromatography Extraction/Inductively Coupled Plasma-Mass Spectrometry (IC-ICP-MS)

Secondary ID

84679

Testing Algorithm

Total arsenic will be performed first. If the total arsenic concentration is 15 mcg/L or greater, then fractionation will be performed and reported.  If total arsenic is below 15 mcg/L, total arsenic will be reported as less than 15 mcg/L and fractionation will not be performed.