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Test Code MISC2MAYOBAPS Bile Acid Profile, Serum


Advisory Information


This test is intended for use by research scientists. Approval must be obtained before ordering.



Specimen Required


Patient Preparation: Patient must be fasting for 12 to 14 hours.

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL


Secondary ID

62538

Useful For

Evaluating the enterohepatic cycle consisting of the biliary system, intestine, portal circulation, and hepatocytes

 

Supporting researchers in need of free and conjugated values of all 20 bile acid species as well as total bile acid

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Bile Acid Profile, S

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 90 days
  Ambient  90 days
  Frozen  90 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Other Nonfasting specimen

Reference Values

Analyte

Normal (nmol/mL)

Chenodeoxycholic acid

≤2.26

Cholic acid

≤2.74

Deoxycholic acid

≤2.84

Dihydroxycholestanoic acid

≤0.07

Glycochenodeoxycholic acid

≤5.14

Glycocholic acid

≤2.17

Glycodeoxycholic acid

≤3.88

Glycohyodeoxycholic acid

≤0.01

Glycolithocholic acid

≤0.11

Glycoursodeoxycholic acid

≤1.00

Hyodeoxycholic acid

≤0.12

Lithocholic acid

≤0.09

Taurochenodeoxycholic acid

≤0.80

Taurocholic acid

≤0.31

Taurodeoxycholic acid

≤0.78

Taurohyodeoxycholic acid

≤0.02

Taurolithocholic acid

≤0.04

Tauroursodeoxycholic acid

≤0.05

Trihydroxycholestanoic acid

≤1.73

Ursodeoxycholic acid

≤0.64

Total bile acids

≤19.00

Day(s) and Time(s) Performed

Monday through Friday; 8 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BAPS Bile Acid Profile, S 43130-4

 

Result ID Test Result Name Result LOINC Value
35802 Chenodeoxycholic acid 30519-3
35801 Cholic acid 30518-5
35803 Deoxycholic acid 30520-1
35819 Dihydroxycholestanoic acid 53479-2
35808 Glycochenodeoxycholic acid 93335-8
35807 Glycocholic acid 93334-1
35809 Glycodeoxycholic acid 93333-3
35811 Glycohyodeoxycholic acid 93332-5
35812 Glycolithocholic acid 93331-7
35810 Glycoursodeoxycholic acid 93330-9
35805 Hyodeoxycholic acid 93329-1
35806 Lithocholic acid 74897-0
35814 Taurochenodeoxycholic acid 93328-3
35813 Taurocholic acid 93327-5
35815 Taurodeoxycholic acid 93326-7
35817 Taurohyodeoxycholic acid 93325-9
35818 Taurolithocholic acid 93324-2
35816 Tauroursodeoxycholic acid 93323-4
35820 Trihydroxycholestanoic acid 38188-9
35804 Ursodeoxycholic acid 55159-8
35821 Total bile acids 14628-2

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.