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Test Code MISC2MAYOCALX CALR Mutation Analysis, Myeloproliferative Neoplasm (MPN), Reflex, Varies

Reporting Name

CALR, Gene Mutation, Exon 9, Reflex

Specimen Type

Varies


Specimen Required


Only orderable as a reflex. For more information see MPNR / Myeloproliferative Neoplasm (MPN), JAK2 V617F with Reflex to CALR and MPL.


Specimen Minimum Volume

Blood and Bone marrow: 0.05 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Varies 7 days

Reference Values

Only orderable as a reflex. For more information see MPNR / Myeloproliferative Neoplasm (MPN), JAK2 V617F with Reflex to CALR and MPL.

 

An interpretive report will be provided.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81219-CALR (calreticulin) (eg, myeloproliferative disorders), gene analysis, common variants in exon 9

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CALX CALR, Gene Mutation, Exon 9, Reflex In Process

 

Result ID Test Result Name Result LOINC Value
36998 Final Diagnosis 22637-3

Method Name

Only orderable as a reflex. For more information see MPNR / Myeloproliferative Neoplasm (MPN), JAK2 V617F with Reflex to CALR and MPL

 

Polymerase Chain Reaction (PCR) and Fragment Analysis

Secondary ID

36997

Useful For

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder

 

Evaluates for mutations in CALR in an algorithmic process for the MPNR / Myeloproliverative Neoplasm (MPN), JAK2 V617F with Reflex to CALR and MPL

Reject Due To

Gross hemolysis

Reject

Other

Paraffin embedded bone marrow aspirate clot or biopsy blocks, slides, paraffin shavings

Moderately to severely clotted

Day(s) and Time(s) Performed

Monday through Friday