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Test Code MISC2MAYOFD2PG Prostaglandin D2 (PGD2)


Specimen Required


Patient preparation:

Patient should NOT be on any aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.

 

Specimen Type: Serum

Container/Tube: Red top

Specimen Volume: 3 mL

Collection Instructions: Draw blood in a plain, red-top tube(s), serum-gel tube(s) is acceptable. Separate immediately and send 3 mL of serum frozen in a plastic vial.


Secondary ID

75492

Method Name

Prostaglandin D2 is measured by EIA/ELISA following extractions of specimens.

Reporting Name

Prostaglandin D2 (PGD2)

Specimen Type

Serum

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen 60 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Other Specimens other than Serum or Plasma EDTA. Test is strict frozen.

Clinical Information

Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and Indomethacin.

Reference Values

Adult Reference Range(s): 35 - 115 pg/mL

 

No pediatric reference ranges available for this test.

Day(s) Performed

Monday through Friday

Report Available

12 to 14 days

Performing Laboratory

Inter Science Institute

Test Classification

This test was performed using a kit that has not been cleared or approved by the FDA and is designated as research use only. The analytic performance characteristics of this test have been determined by Inter Science Institute. This test is not intended for diagnosis or patient management decisions without confirmation by other medically established means.

CPT Code Information

84150

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FD2PG Prostaglandin D2 (PGD2) 12839-7

 

Result ID Test Result Name Result LOINC Value
FD2PG Prostaglandin D2 (PGD2) 12839-7