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Test Code MISC2MAYOKITBM KIT Asp816Val Mutation Analysis, Qualitative PCR, Bone Marrow

Reporting Name

KIT Asp816Val Mutation Analysis, BM

Useful For

Diagnosing systemic mastocytosis in bone marrow specimens

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Bone Marrow


Shipping Instructions


Specimen must arrive within 7 days (168 hours) of collection.



Necessary Information


The following information is required:

1. Pertinent clinical history

2. Clinical or morphologic suspicion

3. Date of collection

4. Specimen source



Specimen Required


Container/Tube: Bone marrow

Preferred: EDTA (lavender top)

Acceptable: ACD-B (yellow top)

Specimen Volume: 2 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube.

3. Label specimen as bone marrow.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Bone Marrow Ambient (preferred) 7 days PURPLE OR PINK TOP/EDTA
  Refrigerated  7 days PURPLE OR PINK TOP/EDTA

Reference Values

An interpretive report will be provided indicating the mutation status as positive or negative.

Day(s) and Time(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81273-KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (eg, mastocytosis), gene analysis, D816 variant(s)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
KITBM KIT Asp816Val Mutation Analysis, BM In Process

 

Result ID Test Result Name Result LOINC Value
34852 Final Diagnosis: 34574-4

Reject Due To

Gross hemolysis Reject
Other Moderately to severely clotted

Method Name

Allele-Specific Oligonucleotide Polymerase Chain Reaction (PCR)

Forms

1. Hematopathology Patient Information (T676) in Special Instructions

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.