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HelpTest Code MISC6MLABSMTX Methotrexate - STAT ONLY
Department
SEND OUTS
Reference Lab Test Number
MTX
Collection Requirements
*For STAT testing only.
Alternate specimen: CSF in a sterile container
Refer To
Primary Collection Container
Red (No Gel)
Alternate Collection Container
Green (Sodium Heparin)
Transport
Serum, plasma, or CSF refrigerated
Preferred Transport Temperature
Refrigerated
Processing
Centrifuge, aliquot serum into a plastic vial, and refrigerate.
Minimum Testing Volume
0.25 mL
Reference Range
A therapeutic range for Methotrexate has not been defined. No precise relationship between methotrexate serum levels and antineoplastic efficacy has been established. Serum concentrations are monitored during high-dose therapy to identify the time when active intervention by leucovorin rescue should be initiated. Serum concentrations indicative of an increased risk of toxicity after a 4-6 hour high-dose infusion are as follows:
24 hr >5.00 umol/L 48 hr >0.50 umol/L 72 hr >0.10 umol/L*Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Methodology
Competitive Enzyme Immunoassay
Performed
Sunday – Saturday
Reported
2 hours
CPT Codes
80299
Unacceptable Conditions
Specimens drawn in an SST or PST tube.
Additional Information
SHIPPING INSTRUCTIONS:
Call U of M Lab (800)862-7284 to notify them of shipment.
Fill out a computer downtime slip to send with specimen.
Include test name and fax number Send Outs (989)583-6796.
Call Yellow Cab 752-3117 to notify them of a STAT pickup for U of M.